Innovotech’s Anti-Encrustation Assay is a high-throughput modified BEST Assay™ method that incorporates 3D modeling to design and produce a testing platform best suited to assess coated urinary catheters or stents for anti-encrustation properties and efficacy.
The testing results in a cost-effective understanding of anti-adherence, anti-biofilm or antimicrobial properties of your medical device sample, tested under in vitro, clinically relevant conditions.
Encrustation are mineral deposits on the surface of medical devices caused primarily by Proteus spp. that may lead to catheter blockage, causing serious infections (i.e., CAUTI (Catheter-Associated Urinary Tract Infection)).
Encrustation formation on medical devices can affect their longevity, safety, and functionality. Our anti-encrustation assays help evaluate materials and coatings under clinically relevant conditions and generate data to support material selection and coating optimization for a safer product launch.
Stents, catheters, and various urological devices can be tested under both intraluminal and extraluminal conditions.
We have several clinical and standard test strains that are pertinent to encrustation including, Proteus mirabilis, Klebsiella pneumoniae, Enterococcus faecalis, Escherichia coli, Staphylococcus aures, Staphylococcus epidermidis, Morganella morganii and more.
We examined different fluid exchange intervals of 24hours and 48hours for both short term and intermediate periods. If you’re unsure, get in touch with us to find out which time points and settings work best for you.
