The substrate changes everything: hydrophobicity, protein conditioning, EPS architecture, antimicrobial penetration, even which species end up dominant. An MIC value generated on a polystyrene plate may say very little about what your antimicrobial will do once a biofilm has matured on a catheter or an implant capsule.
That’s why we built the MBEC Assay with silicone-coated pegs.
Same 96-peg high-throughput format. Same ASTM E2799-22-aligned method. A silicone surface that mirrors the clinical reality your device will face.