Publications
Recent Published Papers
- Michael Harding; Patricia Nadworny; Brenton Buziak; Amin Omar; Greg Daniels; Jie Feng (2019). Improved Methods for Treatment of Phytopathogenic Biofilms: Metallic Compounds as Anti-Bacterial Coatings and Fungicide Tank-Mix Partners. Molecules, Volume 24, Issue 12, 2312. DOI: 10.3390/molecules24122312.
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Amin Omar, J. Barry Wright, Gregory Schultz, Robert Burrell, Patricia Nadworny (2017). Microbial Biofilms and Chronic Wounds. Microorganisms 2017, 5(1), 9;
doi :10.3390/microorganisms5010009. -
Amin Omar, and Patricia Nadworny (2016). Review: Antimicrobial efficacy validation using in vitro and in vivo testing methods. Advanced Drug Delivery Reviews. http://dx.doi.org/10.1016/j.addr.2016.09.003
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Patricia Nadworny, Vanessa Incani, Amin Omar, Graeme Prosperi-Porta, (2015). Ag5IO6: Novel anti-biofilm activity of a silver compound with application to medical devices. International Journal of Antimicrobial Agents. Volume 45, Issue 6, Pages 586–593. DOI: http://dx.doi.org/10.1016/j.ijantimicag.2014.09.008
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Mikel Gray, Amin Omar, Brenton Buziak (2014) Can a Stool Management System Prevent Environmental Spread of Clostridium
Difficile : A Comparative Trial. American Journal of Infection Control. J Wound Ostomy Continence Nurs. 2014 Sep-Oct;41(5):460-5.doi : 10.1097/WON.0000000000000055 -
A.E. Parker, D. K. Walker, D.M. Goeres, N. Allan, M.E. Olson, A. Omar (2014) Ruggedness and reproducibility of the MBEC biofilm disinfectant efficacy test. Journal of Microbiological Methods. Volume 102, July 2014, Pages 55–64. https://doi.org/10.1016/j.mimet.2014.04.013.
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ASTM E2799 – 17 Standard Test Method for Testing Disinfectant Efficacy against Pseudomonas
aeruginosa Biofilm using the MBEC Assay.
Nature Protocols Paper (on the MBEC assay)
- 10 June 2010 – Microtiter susceptibility testing of microbes growing on peg lids: a miniaturized biofilm model for high-throughput screening.
Read the full publication at nature.com
History
- Interspecies variation in Candida biofilm formation studied using the Calgary biofilm device
- Investigating the suitability of the Calgary Biofilm Device for assessing the antimicrobial efficacy of new agents
- The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms
- The MBEC Assay™ System: multiple equivalent biofilms for antibiotic and biocide susceptibility testing
Antibiotic, Antimicrobial and Biocide Resistance
- Biofilm bacteria: formation and comparative susceptibility to antibiotics.
- Persister cells mediate tolerance to metal oxyanions in Escherichia coli.
- High-throughput metal susceptibility testing of microbial biofilms.
- Persister cells, the biofilm matrix and tolerance to metal cations in biofilm and planktonic Pseudomonas
aeruginosa . - Inhibition of Xylella fastidiosa Biofilm Formation via Metal Chelators.
- Co-encapsulation of gallium with gentamicin in liposomes enhances
antimicrobial activity of gentamicin against Pseudomonasaeruginosa . - Pseudomonas
pseudoalcaligenes KF707 upon biofilm formation on a polystyrene surface acquire a strong antibiotic resistance with minor changes in their tolerance to metal cations and metalloid oxyanions. - Oritavancin Kills Stationary-Phase and Biofilm Staphylococcus aureus Cells In Vitro.
- Antibiotic Resistance in Gram-Negative peritonitis.
- Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids.
- Assessing the antimicrobial activity of zinc oxide thin films using disk diffusion and biofilm reactor.
- Antibiofilm efficacy of nitric oxide-releasing silica nanoparticles.
- Activities of Daptomycin and Vancomycin Alone and in Combination with Rifampin and Gentamicin against Biofilm-Forming Methicillin-Resistant Staphylococcus aureus Isolates in an Experimental Model of Endocarditis.
- In Vitro Activities of a Novel Nanoemulsion against Burkholderia and Other Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species.
- Comparative susceptibility of planktonic and 3-day-old Salmonella Typhimurium biofilms to disinfectants.
- Use of Biofilm Model Systems to Study Antimicrobial Susceptibility.
- Growing Burkholderia
pseudomallei in Biofilm Stimulating Conditions Significantly Induces Antimicrobial Resistance.
Agricultural Diseases
- Characterization of Biofilm formation of Xylella fastidiosa In Vitro.
- Biofilms: A new understanding of these microbial communities is driving a revolution that may transform the science of microbiology
- The Evaluation of Commercially Available Disinfectant Combinations on Biofilms for Use in Slaughter Houses (ppt)
- Marques, L. R., Olson, M. E., Ceri, H., Harding, M. W., Allan, N.D., and Earle
,M . L. 2006. Phytopathology. Novel methods for high-throughput screening and efficacy testing of pesticides, fungicidesand disinfectants – Identifying anti-biofilm products. 96
Food Safety
- Development of a standard test to assess the resistance of Staphylococcus aureus biofilm cells to disinfectants.
- In Vitro biofilm formation of commensal and pathogenic Escherichia coli strains: Impact of environmental and genetic factors.
MBEC™
- Characterization of biofilm growth and biocide susceptibility testing of Mycobacterium
phlei using the MBEC Assay™ system. - Minimum inhibitory concentration (MIC) versus
mimimum biofilm eliminating concentration (MBEC) inevaluation ofantibiotic sensitivity of gram-negative bacilli causing peritonitis - Differences in biofilm and planktonic
cell mediated reduction of metalloid oxyanions. - Biofilm susceptibility to metal toxicity
- Metal resistance in Candida biofilms
- Comparative Assessment of the Antimicrobial Susceptibility of Staphylococcus aureus Isolates from Bovine Mastitis in Biofilm Versus Planktonic Culture.
- A novel technique for
evalutating the activity of biocides against biofilm bacteria - High throughput metal susceptibility testing of microbial biofilms
- Persister cells, the biofilm matrix and tolerance to metal cations in biofilm and planktonic Pseudomonas
aeruginosa . - Quorum-Sensing Mutations Affect Attachment and Stability of Burkholderia
cenocepacia Biofilms - The GacS sensor kinase controls phenotypic reversion of small colony variants isolated from biofilms of Pseudomonas
aeruginosa PA14 - Effects of the twin-arginine translocase on the structure and antimicrobial susceptibility of Escherichia coli biofilms
- Quorum-Sensing Mutations Affect Attachment and Stability of Burkholderia
cenocepacia Biofilms. - Investigating the suitability of the Calgary Biofilm Device for assessing the antimicrobial efficacy of new agents.
- Burn Wound Infections.
- Pace, J. L., Rupp, M. E., and R. G. Finch. 2006. Biofilm, Infection, and Antimicrobial Therapy.Coagulase-Negative Staphylococci, Chapter 7: 109-155.
- Pace, J. L., Rupp, M. E., and R. G. Finch. 2006. Biofilm, Infection, and Antimicrobial Therapy.Minimal Biofilm Eradication, Chapter 13.
- Pace, J. L., Rupp, M. E., and R. G. Finch. 2006. Biofilm, Infection, and Antimicrobial Therapy.Biofilms: Background, Significance, and Roles of Catheters and Indwelling Devices. Section 1.
- Study of susceptibility of oral bacteria biofilm to traditional Chinese drug
preventing preventing caries. - The Impact of a cation channel blocker (furosemide) on Pseudomonas
aeruginosa PAO1 biofilm architecture. - Clinical trials in cystic fibrosis.
- Extended antimicrobial susceptibility assays for Staphylococcus aureus
isolate from bovine mastitis growing in biofilms. - Anti-Infectives Partnering & Deal Making.
- Sterile
Peritonities with Monocytic Predominance Secondary to Acute Rejection of a Previously Failed Renal Allograft. - Bacterial biofilms in wounds.
- Biofilm formation on bone grafts and bone graft
substitutes: Comparison of different materials by a standard in vitro test and microcalorimetry. - Inactivation of Vibrio
anguillarum by attached and planktonic Roseobacter.